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University of Pennsylvania
Department of Neuroscience
215 Stemmler Hall, 3450 Hamilton Walk
Philadelphia, PA 19104
Office: 110 Johnson Pavilion
Office phone: 215.746.2790
Lab: 109 Johnson Pavilion
Lab phone: 215.746-2791
Fax: 215.573.9050
E-mail: minghong@mail.med.upenn.edu
Research Interests
The mammalian olfactory system has the remarkable ability to discriminate
thousands of odorants. As the primary neuronal elements in the olfactory
system, olfactory sensory neurons are responsible for detecting odor
molecules and subsequently sending signals to the brain. These neurons
selectively express one or a few olfactory receptor genes from a repertoire
of ~1000, the largest gene family in the mammalian genome. We are interested
in the functional and molecular organization of the olfactory system
and the mechanisms underlying olfactory coding and processing. Our approach
combines techniques from different disciplines including optical imaging,
patch clamp recording, immunohistochemistry, molecular cloning, in situ
hybridization and Affymetrix genechip.
Graduate Groups
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